Administrative Case Reports
Comparative Technology Guide
A side-by-side educational comparison of available thermal neurolytic treatments. Details on the clinical application, mechanism of action, safety profile and more for each of cryoablation, cryoneurolysis, and cooled/conventional radiofrequency (RF) abalation.
Superficial Genicular Pre-TKA
A case report featuring Dr. Josh Urban performing superficial genicular treatment prior to a Total Knee Arthroplasty using the Smart Tip 190 under ultrasound.
Rib Fracture Intercostal Pain
This case report represents the individual experience of Dr. Pieter Vreede and is intended to demonstrate his methodology for using iovera° to treat rib fracture pain.
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Additional Information
Pacira Pharmaceuticals, Inc.
A subsidiary of Pacira Biosciences, Inc.
10410 Science Center Drive, Building A
San Diego, CA 92121 U.S.A
Legal Disclaimer
Zimmer Biomet acquired the iovera° business from Pacira BioSciences, Inc. on 31 Jul 2026, obtaining contractual agreement for the development, manufacture, and commercialization of iovera°.
During the transition period under the applicable Transition Services Agreement, Pacira remains the legal manufacturer for applicable iovera° products and retains the related regulatory responsibilities.
Zimmer Biomet acts as a contracted service provider, performing certain design, manufacturing, quality, and post-market activities under Pacira's quality system and oversight until the transition is complete.