See how iovera° therapy works on the nerves that transmit pain signals
Dr. Pieter Vreede identifies the parts of the nerve where iovera° takes effect, the surrounding tissue, and structures that remain intact.
A closer look at the effect iovera° therapy has on cells inside the nerve.
See iovera°
in action
Compare nerve
treatments
Additional Information
Pacira Pharmaceuticals, Inc.
A subsidiary of Pacira Biosciences, Inc.
10410 Science Center Drive, Building A
San Diego, CA 92121 U.S.A
Legal Disclaimer
Zimmer Biomet acquired the iovera° business from Pacira BioSciences, Inc. on 31 Jul 2026, obtaining contractual agreement for the development, manufacture, and commercialization of iovera°.
During the transition period under the applicable Transition Services Agreement, Pacira remains the legal manufacturer for applicable iovera° products and retains the related regulatory responsibilities.
Zimmer Biomet acts as a contracted service provider, performing certain design, manufacturing, quality, and post-market activities under Pacira's quality system and oversight until the transition is complete.