Many of your patients can benefit from the long-lasting pain relief of the iovera° treatment
- OA knee pain
- Patients with moderate OA chronically cycling through NSAIDs, injections, and opioids
- Pre-TKA prehabilitation and TKA rehabilitation and recovery
- Patients who are planning for TKA surgery and want to recover and rehab with targeted pain relief
- Patients who hesitate or wish to delay surgery (eg, until after an event or season)
- Patients concerned with pain limiting their postsurgical rehabilitation
- Patients with risk factors that need to be addressed prior to TKA
- Patients determined not to be surgical candidates (eg, high risk)
- Other areas of the body
- iovera° is being used for pain in areas including the hip, shoulder, ribs, foot and ankle, spine, and occipital
NSAID=non-steroidal anti-inflammatory drug; OA=osteoarthritis; TKA=total knee arthroplasty.
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Additional Information
Pacira Pharmaceuticals, Inc.
A subsidiary of Pacira Biosciences, Inc.
10410 Science Center Drive, Building A
San Diego, CA 92121 U.S.A
Legal Disclaimer
Zimmer Biomet acquired the iovera° business from Pacira BioSciences, Inc. on 31 Jul 2026, obtaining contractual agreement for the development, manufacture, and commercialization of iovera°.
During the transition period under the applicable Transition Services Agreement, Pacira remains the legal manufacturer for applicable iovera° products and retains the related regulatory responsibilities.
Zimmer Biomet acts as a contracted service provider, performing certain design, manufacturing, quality, and post-market activities under Pacira's quality system and oversight until the transition is complete.