Patents
This website is provided to satisfy the virtual patent marking provisions of various jurisdictions including the virtual patent marking provisions of the America Invents Act and is intended to serve as notice under 35 U.S.C. § 287(a).
The iovera° system including its components are covered by or for use under one or more of the listed U.S. patents and foreign equivalents. Additional Pacira BioSciences, Inc. patents are pending in the United States and foreign jurisdictions. The following list may not be all inclusive, and other Pacira products not listed here may be protected by one or more patents.
The following Pacira products are protected by patents in the United States and elsewhere.
The iovera° system is protected by U.S. Patents:
- 11,350,979
- 11,311,327
- 11,272,972
- 11,253,393
- 11,134,999
- 10,939,947
- 10,888,366
- 10,869,779
- 10,864,112
- 10,864,033
- 10,596,030
- 10,470,813
- 10,363,080
- 10,314,739
- 10,130,409
- 10,085,789
- 10,016,229
- 9,907,693
- 9,668,800
- 9,610,112
- 9,345,526
- 9,295,512
- 9,101,346
- 9,072,498
- 9,066,712
- 9,017,318
- 8,715,275
- 8,298,216
- D732739
- D702848
- D683733
Additional patents may be pending in the United States and elsewhere.
The iovera° system is not currently for sale in the United States for the treatment of wrinkles.
Indication
The iovera° system is used to destroy tissue during surgical procedures by applying freezing cold. It can also be used to produce lesions in peripheral nervous tissue by the application of cold to the selected site for the blocking of pain. It is also indicated for the relief of pain and symptoms associated with osteoarthritis of the knee for up to 90 days. The iovera° system is not indicated for treatment of central nervous system tissue.
When stimulation compatible components are used, the iovera° system can also facilitate target nerve location by conducting electrical nerve stimulation from a compatible 3rd party nerve stimulator.
Important Safety Information
Contraindications
The iovera° system is contraindicated for use in patients with the following:
- Cryoglobulinemia, paroxysmal cold hemoglobinuria, cold urticaria, Raynaud’s disease, and open and/or infected wounds at or near the treatment site
Potential Complications
As with any surgical treatment that uses needle-based therapy and local anesthesia, there is a potential for site-specific reactions, including, but not limited to:
- Ecchymosis, edema, erythema, local pain and/or tenderness, and localized dysesthesia
Proper use of the device as described in the User Guide can help reduce or prevent the following complications:
- At the treatment site(s): injury to the skin related to application of cold or heat, hyper- or hypopigmentation, and skin dimpling
- Outside the treatment site(s): loss of motor function
Indication
The iovera° system is used to destroy tissue during surgical procedures by applying freezing cold. It can also be used to produce lesions in peripheral nervous tissue by the application of cold to the selected site for the blocking of pain.
Important Safety Information