Videos and assets detailing how to set up the system, the mechanism of action (MOA), procedural protocols, and more

WHY iovera°

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Modalities Affecting Pain in the Body

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History of Cryotechnology and Introduction of the iovera° System

iovera° SYSTEM

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Nerve Anatomy Related to the iovera° MOA vs Other Modalities

MODALITIES

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MOA Video

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Efficacy and Safety of iovera°

iovera° FOR OA KNEE & PRE-TKA

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How iovera° Fits With the Treatment of TKA Pain

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Considering Knee Anatomy for Treatment of Pain

SAMPLE TREATMENTS

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Anatomical Landmark Treatment Technique

iovera° SYSTEM SETUP

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Gen 1 System Guide

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Gen 2 System Guide

Administrative Case Reports

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Comparative Technology Guide

A side-by-side educational comparison of available thermal neurolytic treatments. Details on the clinical application, mechanism of action, safety profile and more for each of cryoablation, cryoneurolysis, and cooled/conventional radiofrequency (RF) abalation.

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Superficial Genicular Pre-TKA

A case report featuring Dr Josh Urban performing superficial genicular treatment prior to a Total Knee Arthroplasty using the Smart Tip 190 under ultrasound.

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Rib Fracture Intercostal Pain

This case report represents the individual experience of Dr Pieter Vreede and is intended to demonstrate his methodology for using iovera° to treat rib fracture pain.

See iovera° in action

Get helpful information about iovera°

Indication

The iovera° system is used to destroy tissue during surgical procedures by applying freezing cold. It can also be used to produce lesions in peripheral nervous tissue by the application of cold to the selected site for the blocking of pain. It is also indicated for the relief of pain and symptoms associated with osteoarthritis of the knee for up to 90 days. The iovera° system is not indicated for treatment of central nervous system tissue.

When stimulation compatible components are used, the iovera° system can also facilitate target nerve location by conducting electrical nerve stimulation from a compatible 3rd party nerve stimulator.

Important Safety Information

Contraindications

The iovera° system is contraindicated for use in patients with the following:

  • Cryoglobulinemia, paroxysmal cold hemoglobinuria, cold urticaria, Raynaud’s disease, and open and/or infected wounds at or near the treatment site

Potential Complications

As with any surgical treatment that uses needle-based therapy and local anesthesia, there is a potential for site-specific reactions, including, but not limited to:

  • Ecchymosis, edema, erythema, local pain and/or tenderness, and localized dysesthesia

Proper use of the device as described in the User Guide can help reduce or prevent the following complications:

  • At the treatment site(s): injury to the skin related to application of cold or heat, hyper- or hypopigmentation, and skin dimpling
  • Outside the treatment site(s): loss of motor function
More +

Indication

The iovera° system is used to destroy tissue during surgical procedures by applying freezing cold. It can also be used to produce lesions in peripheral nervous tissue by the application of cold to the selected site for the blocking of pain.

Important Safety Information